Significance of Subcutaneous Nodules in Rheumatoid Arthritis

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The significance of subcutaneous nodules in rheumatoid arthritis.

The presence of subcutaneous nodules in rheumatic fever is of serious prognostic significance because, as they are pathologically similar to the Aschoff bodies found in the heart, they generally indicate severe cardiac damage and active infection. As a rule nodules appear after the onset of the rheumatic heart lesion. There is, therefore, practically always cardiac involvement in cases where no...

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Subcutaneous nodules in rheumatoid arthritis.

A 29 year old male with rheumatoid arthritis (RA) of 10 years duration presented with multiple subcutaneous nodules of one month duration while on methotrexate (7.5 mg once a week), salazopyrine (1000 mg/day) and methyl prednisolone (4 mg/day). The nodules involved tendons of metacarpophalangeal joints (Figure 1) and base of left great toe (Figure 2), were painless and did not interfere with hi...

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Subcutaneous Nodules of Rheumatoid Arthritis with Lipoid Deposition.

Weber and Freudenthal (1936-7), Weber (1943, 1944, 1947, 1948), and Fletcher (1946, 1947) have noted the rare occurrence of subcutaneous nodules in rheumatoid arthritis which consisted almost entirely of lipoid, and have designated such cases by various names to differentiate them from the " common " type of rheumatoid arthritis subcutaneous nodule. During the clinical examination of seventy ca...

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Subcutaneous Rheumatoid Nodules.

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Subcutaneous rheumatoid nodules.

We describe seven children with subcutaneous rheumatoid nodules who had no clinical evidence of rheumatoid arthritis. Only one girl was seropositive for antinuclear factors and had a slightly raised erythrocyte sedimentation rate. Clinical aspects, risks for developing rheumatoid arthritis, and treatment of this entity are discussed.

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1947

ISSN: 0003-4967

DOI: 10.1136/ard.6.4.219